← All Compounds
Mechanism Decapeptide fragment of kisspeptin that activates KISS1R (GPR54) in hypothalamic GnRH neurons. Potently stimulates LH and FSH secretion, serving as a key regulator of the reproductive hormone axis. Half-Life Approximately 4 minutes (IV), 27 minutes (SC) Route subcutaneous Frequency Single dose (weight-based: 1-10 mcg/kg)
FDA Category Research peptide (FDA Category 2) Reclassification pending Date Restricted 2023-09-29 Announced Return 2026-02-27
Inclusion of a compound does not constitute endorsement. Information sourced from published research and regulatory filings.
Kisspeptin-10
Cat 2 → Pending Cat 1Longevity & Immune · Research peptide (multiple suppliers)
Decapeptide fragment of kisspeptin researched for reproductive hormone axis regulation. Not FDA-approved for any indication.
About
Clinical Dosing
75-750 mcgsingle dose (weight-based: 1-10 mcg/kg)
Not FDA-approved. Investigational use in reproductive endocrinology. Currently FDA Category 2 (restricted). Pending return to Category 1.
Dosing extrapolated from animal studies and community protocols. No large-scale human clinical trials.
Regulatory Status
Status based on publicly available FDA communications. Verify at FDA.gov for authoritative guidance.
View full regulatory timeline →Titration Protocols
Research Protocol
Source: Dhillo et al., Journal of Clinical Endocrinology & Metabolism, 2005
| Dose | Duration | Draw (1 mg vial in 2mL) | Notes |
|---|---|---|---|
| 1 mcg | Maintenance | 0.00 mL (< 1 units) | Single SC dose (research); dose varies by protocol |
Available Vial Sizes
1 mg
1 mg vial
5 mg
5 mg vial
Citations
- [1]Kisspeptin-54 Stimulates the Hypothalamic-Pituitary-Gonadal Axis in Human Males. Journal of Clinical Endocrinology & Metabolism, 90(12), 6609-6615. Link(Reviewed: 2026-02-27)