Peply

Compounds

Compound Reference

Published clinical data, titration protocols, and regulatory status for referenced peptides and injectables.

27 compounds

Neuropeptide
FDA Approved (Vyleesi)

Bremelanotide, Vyleesi

Synthetic cyclic heptapeptide, non-selective melanocortin receptor agonist with preferential activity at MC4R. Activates central nervous...

1.75 mg|As needed, max 1 dose per 24 h
GLP-1 Agonist
FDA Approved

Ozempic, Wegovy

Mimics GLP-1 to enhance insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite via...

0.25-2.4 mg|Once weekly
Growth Hormone
FDA Approved

Egrifta, Egrifta SV

Synthetic analog of human growth hormone-releasing factor (GRF 1-44). Binds to GRF receptors in the...

2 mg|Once daily
Dual Agonist
FDA Approved

Mounjaro, Zepbound

Activates both GIP and GLP-1 receptors, enhancing insulin secretion, suppressing glucagon, slowing gastric emptying, and...

2.5-15 mg|Once weekly
Growth & Recovery
Removed from Cat 2

Body Protection Compound-157

Gastric pentadecapeptide. Promotes angiogenesis, supports tendon and ligament healing, and modulates nitric oxide signaling and...

200-800 mcg|1-2x daily
Neuropeptide
Removed from Cat 2

Dihexa, Dihexa Acetate

Synthetic oligopeptide derived from angiotensin IV. Acts as a hepatocyte growth factor (HGF) mimetic and...

8-45 mg|Once daily (oral, community-derived)
Neuropeptide
Removed from Cat 2

Delta Sleep-Inducing Peptide, Emideltide

Nonapeptide known for modulating sleep architecture and promoting delta-wave sleep. Acts on multiple targets including...

100-300 mcg|Once daily (before sleep)
Longevity & Immune
Removed from Cat 2

Epithalon, Epithalone

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) analog of epithalamin that activates telomerase and may support pineal gland function...

5-10 mg|Daily in 10-day cycles
Growth & Recovery
Removed from Cat 2

Copper Peptide GHK, Glycyl-L-histidyl-L-lysine

Naturally occurring copper-binding tripeptide. Stimulates collagen synthesis, promotes wound healing, has anti-inflammatory and antioxidant properties....

1-3 mg|Once daily
Longevity & Immune
Removed from Cat 2

Lysine-Proline-Valine, Alpha-MSH Fragment

C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH). Potent anti-inflammatory activity via NF-kB inhibition and PGE2...

200-500 mcg|Once daily
Longevity & Immune
Removed from Cat 2

Cathelicidin, hCAP-18

The only known human cathelicidin antimicrobial peptide. 37-amino-acid peptide naturally produced by neutrophils, epithelial cells,...

100-500 mcg|Once daily (community-derived, highly variable)
Neuropeptide
Removed from Cat 2

MT-II, Melanotan 2

Synthetic cyclic peptide analog of α-melanocyte-stimulating hormone (α-MSH). Non-selective agonist of melanocortin receptors (MC1R, MC3R,...

0.25-1 mg|Once daily (community-derived, highly variable)
GH Secretagogue
Investigational

Ibutamoren, MK-0677

Non-peptide ghrelin mimetic. Agonist at the growth hormone secretagogue receptor (GHS-R1a). Increases pulsatile GH release...

10-25 mg|Once daily, oral
Longevity & Immune
Removed from Cat 2

MOTS-C, Mitochondrial ORF of the 12S rRNA Type-C

Mitochondrial-derived peptide encoded within the 12S rRNA gene. Activates AMPK pathway, enhances glucose uptake, improves...

5-10 mg|3-5x/week
Neuropeptide
Removed from Cat 2

ACTH 4-10 analog

Synthetic analog of ACTH (4-10) fragment. Enhances BDNF expression, modulates dopaminergic and serotonergic systems, provides...

200-600 mcg|Once daily (intranasal or SC)
Growth & Recovery
Removed from Cat 2

Thymosin Beta-4, TB4

Synthetic fragment of Thymosin Beta-4. Upregulates actin, promotes cell migration and differentiation, reduces inflammation, and...

2-5 mg|2x/week (loading), 1x/week (maintenance)
Triple Agonist
Investigational

LY3437943

Activates three receptors simultaneously: GIP (enhances insulin), GLP-1 (suppresses appetite, slows gastric emptying), and glucagon...

2-12 mg|Once weekly
Metabolic
Category 1

5-amino-1-methylquinolinium

Selectively inhibits nicotinamide N-methyltransferase (NNMT), preserving nicotinamide for NAD+ synthesis, activating SIRT1 pathways, promoting mitochondrial...

150-500 mcg|Once daily SC (oral: 50-150 mg/day)
Growth & Recovery
Cat 2 → Pending Cat 1

Anti-Obesity Drug 9604, hGH Fragment 176-191

Modified fragment of human growth hormone (amino acids 176-191). Stimulates lipolysis and inhibits lipogenesis without...

250-500 mcg|Once daily
GH Secretagogue
Cat 2 → Pending Cat 1

Modified GRF 1-29, Mod GRF 1-29

Synthetic analog of growth hormone-releasing hormone (GHRH). Stimulates pulsatile GH release from the pituitary. The...

100-300 mcg|2-3x daily
GH Secretagogue
Cat 2 → Pending Cat 1

CJC-1295 DAC, Drug Affinity Complex CJC-1295

GHRH analog with a Drug Affinity Complex (DAC) that extends its half-life by binding to...

1-2 mg|Once weekly
Growth & Recovery
Category 1

Long R3 IGF-1, Long Arginine 3-IGF-1

Long-acting analog of IGF-1 with an extended N-terminal peptide (arginine substitution at position 3 +...

20-100 mcg|Once daily (often post-workout)
GH Secretagogue
Cat 2 → Pending Cat 1

Selective growth hormone secretagogue peptide. Binds ghrelin/GHS receptors in the pituitary to stimulate GH release...

100-300 mcg|2-3x daily
Longevity & Immune
Cat 2 → Pending Cat 1

KP-10, Metastin 45-54

Decapeptide fragment of kisspeptin that activates KISS1R (GPR54) in hypothalamic GnRH neurons. Potently stimulates LH...

75-750 mcg|Single dose (weight-based: 1-10 mcg/kg)
Neuropeptide
Cat 2 → Pending Cat 1

TP-7

Synthetic analog of the immunomodulatory peptide tuftsin with a stabilizing Pro-Gly-Pro sequence. Modulates GABA-A receptor...

200-400 mcg|Once daily (intranasal or SC)
GH Secretagogue
Previously Approved

GRF 1-29, Geref

GHRH analog (GRF 1-29). Binds pituitary GHRH receptors to stimulate endogenous growth hormone release in...

200-500 mcg|Daily before bed
Growth & Recovery
Cat 2 → Pending Cat 1

Ta1, Zadaxin

Naturally occurring thymic peptide. Enhances T-cell maturation and function, activates dendritic cells, augments antibody responses....

1.6-3.2 mg|2x/week