Compound Reference

Ozempic, Wegovy

GLP-1 Agonist

Mimics GLP-1 to enhance insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite via hypothalamic signaling.

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Mounjaro, Zepbound

Dual Agonist

Activates both GIP and GLP-1 receptors, enhancing insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite through complementary incretin pathways.

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LY3437943

Triple Agonist

Activates three receptors simultaneously: GIP (enhances insulin), GLP-1 (suppresses appetite, slows gastric emptying), and glucagon (increases energy expenditure and hepatic fat oxidation). The glucagon component distinguishes it from dual agonists.

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Egrifta, Egrifta SV

Growth Hormone

Synthetic analog of human growth hormone-releasing factor (GRF 1-44). Binds to GRF receptors in the pituitary to stimulate endogenous growth hormone synthesis and release, preserving the pulsatile secretion pattern.

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Body Protection Compound-157

Growth & Recovery

Gastric pentadecapeptide. Promotes angiogenesis, tendon/ligament healing, and nitric oxide signaling. Modulates growth factor expression.

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Thymosin Beta-4, TB4

Growth & Recovery

Synthetic fragment of Thymosin Beta-4. Upregulates actin, promotes cell migration and differentiation, reduces inflammation, and supports tissue repair.

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Copper Peptide GHK, Glycyl-L-histidyl-L-lysine

Growth & Recovery

Naturally occurring copper-binding tripeptide. Stimulates collagen synthesis, promotes wound healing, has anti-inflammatory and antioxidant properties. Activates tissue remodeling genes.

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Anti-Obesity Drug 9604, hGH Fragment 176-191

Growth & Recovery

Modified fragment of human growth hormone (amino acids 176-191). Stimulates lipolysis and inhibits lipogenesis without affecting IGF-1 levels or insulin sensitivity.

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Ta1, Zadaxin

Growth & Recovery

Naturally occurring thymic peptide. Enhances T-cell maturation and function, activates dendritic cells, augments antibody responses. Modulates cytokine production.

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GH Secretagogue

Selective growth hormone secretagogue peptide. Binds ghrelin/GHS receptors in the pituitary to stimulate GH release without significantly affecting cortisol, prolactin, or ACTH levels.

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Modified GRF 1-29, Mod GRF 1-29

GH Secretagogue

Synthetic analog of growth hormone-releasing hormone (GHRH). Stimulates pulsatile GH release from the pituitary. The "no DAC" variant has a shorter duration and preserves natural GH pulsatility.

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CJC-1295 DAC, Drug Affinity Complex CJC-1295

GH Secretagogue

GHRH analog with a Drug Affinity Complex (DAC) that extends its half-life by binding to albumin. Produces sustained, elevated GH and IGF-1 levels rather than pulsatile release.

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ACTH 4-10 analog

Neuropeptide

Synthetic analog of ACTH (4-10) fragment. Enhances BDNF expression, modulates dopaminergic and serotonergic systems, provides neuroprotective effects. Does not affect adrenal cortex function despite ACTH origin.

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TP-7

Neuropeptide

Synthetic analog of the immunomodulatory peptide tuftsin with a stabilizing Pro-Gly-Pro sequence. Modulates GABA-A receptor expression, enhances enkephalin levels, and provides anxiolytic effects without sedation or dependence.

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Delta Sleep-Inducing Peptide, Emideltide

Neuropeptide

Nonapeptide that modulates sleep architecture. Acts on multiple targets including GABA-A receptors, serotonergic pathways, and cortisol regulation. Promotes delta-wave sleep onset without causing sedation.

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Epithalon, Epithalone

Longevity & Immune

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) analog of epithalamin. Activates telomerase, the enzyme responsible for maintaining telomere length. May promote pineal gland function and melatonin production.

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Mitochondrial-Derived Peptide MOTS-c

Longevity & Immune

Mitochondrial-derived peptide encoded within the 12S rRNA gene. Activates AMPK pathway, enhances glucose uptake, improves insulin sensitivity, and regulates cellular metabolism. Functions as a mitochondrial signaling molecule.

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Lysine-Proline-Valine, Alpha-MSH Fragment

Longevity & Immune

C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH). Potent anti-inflammatory activity via NF-kB inhibition and PGE2 reduction. Modulates gut inflammation and mucosal immune response.

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KP-10, Metastin 45-54

Longevity & Immune

Decapeptide fragment of kisspeptin that activates KISS1R (GPR54) in hypothalamic GnRH neurons. Potently stimulates LH and FSH secretion, serving as a key regulator of the reproductive hormone axis.

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5-amino-1-methylquinolinium

Metabolic

Selectively inhibits nicotinamide N-methyltransferase (NNMT), preserving nicotinamide for NAD+ synthesis, activating SIRT1 pathways, promoting mitochondrial biogenesis, and enhancing fat oxidation. Note: This is a small molecule, not a peptide.

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Long R3 IGF-1, Long Arginine 3-IGF-1

Growth & Recovery

Long-acting analog of IGF-1 with an extended N-terminal peptide (arginine substitution at position 3 + 13-amino-acid extension). Reduced binding to IGF binding proteins (IGFBPs) results in longer half-life and greater bioavailability. Promotes muscle hyperplasia, protein synthesis, and glucose uptake in muscle tissue.

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