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TB-500

Cat 2 → Pending Cat 1

Growth & Recovery · Research peptide (multiple suppliers)

Synthetic fragment of Thymosin Beta-4 researched for tissue repair, cell migration, and anti-inflammatory effects. Not FDA-approved for any indication.


About

Mechanism
Synthetic fragment of Thymosin Beta-4. Upregulates actin, promotes cell migration and differentiation, reduces inflammation, and supports tissue repair.
Half-Life
Estimated 2-3 hours
Route
subcutaneous
Frequency
2x/week (loading), 1x/week (maintenance)

Clinical Dosing

2-5 mg2x/week (loading), 1x/week (maintenance)

Not FDA-approved for any indication. Currently FDA Category 2 (restricted). Pending return to Category 1 availability.

Dosing extrapolated from animal studies and community protocols. No large-scale human clinical trials.


Regulatory Status

FDA Category
Research peptide (FDA Category 2)
Reclassification
pending
Date Restricted
2023-09-29
Announced Return
2026-02-27

Status based on publicly available FDA communications. Verify at FDA.gov for authoritative guidance.

View full regulatory timeline →

Titration Protocols

Loading/Maintenance Protocol

Source: Community protocol (loading/maintenance). Goldstein et al., 2012 is a review of Thymosin Beta-4 biology, not a clinical dosing study.

DoseDurationDraw (2 mg vial in 2mL)Notes
4 mg4 weeks4.00 mL (400 units)Loading phase 2x/week
2.5 mgMaintenance2.50 mL (250 units)Maintenance 1x/week

Available Vial Sizes

2 mg

2 mg vial

5 mg

5 mg vial

10 mg

10 mg vial


Citations

  1. [1]Thymosin Beta-4: A Multi-Functional Regenerative Peptide. Expert Opinion on Biological Therapy, 12(1), 37-51. Link(Reviewed: 2026-02-27)